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PRIME - The multidimensional path to the Proteome
Reach for the Full Potential of Proteomics.
Open Your Eyes to PRIME
The Proteome is far more complex than was ever expected at the genesis of the Proteomics revolution. Dynamics in time, space and concentration as well as variability due to modifications and mutations require novel and complementary approaches to generate useful, reliable and complete information. There is no „one size fits all“ in unraveling the Proteome. PRIME delivers a multidimensional toolbox to unlock the complexity.
Protemics through Integrated MALDI and ESI
Bruker’s PRIME solution (Protemics through Integrated MALDI and ESI) leads the way to integrated approaches for modern proteomics and harnesses the strengths of a range of mass spectrometry technologies as well as bioinformatics without compromises. This results in enhanced protein identification and data rich interpretation about the proteome.
A multi-tier approach to turn proteome data into knowledge
Highest Level of Proteome Analysis
Novel approaches like including Glycomics, PTM analysis and MALDI Molecular Imaging are fully embedded. PRIME moves you, without technology compromises, to the highest level of proteome analysis.
Bioinformatics: ProteinScape
In PRIME, ProteinScape, Bruker‘s market-leading proteomics database system, enables data analysis at an unsurpassed level of efficiency for protein identification, quantitation and PTM characterization, as well as detailed reporting in accordance with publication
guidelines.
The no compromise solution for Proteomics
PRIME is a no compromise solution - PRIME features the combination of data from most current mass spectrometry technologies. PRIME includes leading bioinformatics tools to provide enhanced protein identification and data rich proteome interpretation.
maxis impact, maxis 4G UHR-QTOF
- Ultimate combination of high resolution, mass accuracy, speed and senstivity
- Unlimited m/z for Top-down analysis of intact proteins and non-covalent protein complexes
autoflex speed, ultrafleXtreme MALDI-TOF/TOF
- Bottom-up LC-MALDI with high dynamic range and no time contraints
- Top-down analysis of proteins
- Glycopeptide classification and complete structure elucidation
- MALDI Molecular Imaging on tissue
- Ultrafast MS/MS speed for high sequence coverage in Bottom-up proteomics
- ETD analysis of post-translationally modified peptides
- Top-down ETD/PTR of intact proteins
- Robust and reliable plug-and-play nano/cap-ESI source (50 – 5000 nL/min)
- High transmission by focusing the ion plume into the MS orifice
- Splitless nanoUHPLC system (up to 10,000 psi) for 1D and 2D separations
- Reliable, reproducible and robust to maximize MS utilization time
ProteinScape bioinformatic suite
- Market-leading proteomics data analysis system
- Highly integrative tools for in-depth knowledge retrieval
- Archiving and reporting according to standard guidelines
Related products
amaZon speed seriesESI-TOF-seriesUHR-TOF series, maXissolariX series
Further reading
Brochure PRIME - The multidimensional path to the Proteome
Application Note - 2500 Protein Identified from a Human cell Lysate with Complementary MALDI and ESI Data
Application Note - Biomarker Discovery and Identification by MALDI Molecular Tissue Imaging and Top-down Sequencing
